The majority of the current buildings date to the late 20th century and are depicted on OS sheets as a 'Research Laboratory', however the complex retains the large house in the gardens of which the research buildings have been constructed. Partial legibility of Knowle House dating to the early 19th century (Harman and Minnis 2004, 216). The boundaries of this plot (only partly built over by the present complex probably date to at least the disparkment of Sheffield Great Park in the early 18th century.