Buckley, M., Anderung, C., Penkman, K., Raney, B., Götherström, A., Thomas-Oates, J. and Collins, M. J. (2008). Comparing the survival of osteocalcin and mtDNA in archaeological bone from four European sites. J Archaeol Sci 35 (6). Vol 35(6), pp. 1756-1764.
Title The title of the publication or report |
Comparing the survival of osteocalcin and mtDNA in archaeological bone from four European sites | |||
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Issue The name of the volume or issue |
J Archaeol Sci 35 (6) | |||
Series The series the publication or report is included in |
Journal of Archaeological Science | |||
Volume Volume number and part |
35 (6) | |||
Page Start/End The start and end page numbers. |
1756 - 1764 | |||
Biblio Note This is a Bibliographic record only. |
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Publication Type The type of publication - report, monograph, journal article or chapter from a book |
Journal | |||
Abstract The abstract describing the content of the publication or report |
The small mineral-binding bone protein, osteocalcin, has been applied in a number of studies on ancient bone due to predictions of its long-term stability. However, the intact protein has not been shown to survive in ancient bone devoid of DNA, which is a much more phylogenetically informative biomolecule. In this investigation, the survival of osteocalcin is directly compared to the amplification of mtDNA in a set of thirty-four archaeological samples from four sites throughout Europe. The authors also present unpublished osteocalcin sequences of seven mammalian species in addition to the nineteen published sequences to highlight phylogenetic limitations of this protein. The results indicate that the intact osteocalcin molecule survives less in archaeological samples than mtDNA and is more subject to the temperature of the archaeological site. Amino acid analyses show the persistence of the dominant protein collagen in samples that failed both osteocalcin and mtDNA analyses. The implications these findings present for biomolecular species identification in archaeological and palaeontological material are that, although proteins do survive beyond ancient DNA, osteocalcin does not appear to be the most ideal target (German, Greek and Spanish data). | |||
Year of Publication The year the book, article or report was published |
2008 | |||
Locations Any locations covered by the publication or report. This is not the place the book or report was published. |
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Source Where the record has come from or which dataset it was orginally included in. |
BIAB
(The British & Irish Archaeological Bibliography (BIAB))
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Relations Other resources which are relevant to this publication or report |
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Created Date The date the record of the pubication was first entered |
23 Jul 2008 |