Brickley, M. B., Mays, S. and Ives, R. (2005). Skeletal manifestations of vitamin D deficiency osteomalacia in documented historical collections. Internat J Osteoarchaeol 15 (6). Vol 15(6), pp. 389-403.

Title
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Title:
Skeletal manifestations of vitamin D deficiency osteomalacia in documented historical collections
Issue
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Internat J Osteoarchaeol 15 (6)
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Series:
International Journal of Osteoarchaeology
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Volume:
15 (6)
Page Start/End
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Page Start/End:
389 - 403
Biblio Note
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Abstract
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It is suggested that the frequency with which changes related to vitamin D deficiency are recorded in juvenile bone from archaeological contexts makes it clear that conditions conducive to such deficiency were fairly widespread at a number of points in the past, and that although changes will take longer to be manifest in the adult skeleton than in juveniles, and may not be as obvious, the scarcity of reported cases suggests that it is likely that cases of osteomalacia are being overlooked in archaeological human bone. Vitamin D is probably better described as a hormone, rather than a vitamin, and the production of vitamin D within the body following exposure to sunlight allows adequate mineralisation of bone to take place. Lack of exposure to sunlight, which can be caused by a range of factors, is probably one of the main causes of vitamin D deficiency. The result of such a deficiency is a general weakening of the skeleton. The range of skeletal changes recorded across different bones of the skeleton in two documented historical pathology collections (the Galler collection, Basel, and the collection of the Federal Museum for Pathological Anatomy, Vienna), are discussed for scapulae, vertebrae, ribs, sterna, pelves and femora. The likelihood of each feature being preserved in archaeological skeletal material is considered. Although the changes associated with osteomalacia may lead to fragmentation of the skeleton, it is suggested that the presence of characteristic changes on bones from across the skeleton should make the condition identifiable using macroscopic examination, even where the skeleton is not well preserved. The identification of cases of osteomalacia in archaeological skeletal material is potentially significant because of the socio-cultural information that can be implied from diagnosis of the condition.
Author
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Author:
Megan B Brickley
Simon Mays
R Ives
Year of Publication
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Year of Publication:
2005
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Subjects / Periods:
Archaeological Skeletal Material (Auto Detected Subject)
Juvenile Bone (Auto Detected Subject)
Bone (Auto Detected Subject)
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BIAB (The British & Irish Archaeological Bibliography (BIAB))
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URI: http://www3.interscience.wiley.com/cgi-bin/abstract/112157276/ABSTRACT
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04 May 2007