Mays, S. and Taylor, G. M. (2002). Osteological and biomolecular study of two possible cases of hypertrophic osteoarthropathy from mediaeval England. J Archaeol Sci 29 (11). Vol 29(11), pp. 1267-1276.
Title The title of the publication or report |
Osteological and biomolecular study of two possible cases of hypertrophic osteoarthropathy from mediaeval England | ||||
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Issue The name of the volume or issue |
J Archaeol Sci 29 (11) | ||||
Series The series the publication or report is included in |
Journal of Archaeological Science | ||||
Volume Volume number and part |
29 (11) | ||||
Page Start/End The start and end page numbers. |
1267 - 1276 | ||||
Biblio Note This is a Bibliographic record only. |
Please note that this is a bibliographic record only, as originally entered into the BIAB database. The ADS have no files for download, and unfortunately cannot advise further on where to access hard copy or digital versions. | ||||
Publication Type The type of publication - report, monograph, journal article or chapter from a book |
Journal | ||||
Abstract The abstract describing the content of the publication or report |
Studies two skeletons from medieval Wharram Percy, North Yorkshire, which show osteological lesions consistent with hypertrophic osteoarthropathy. The primary cause of hypertrophic osteoarthropathy is generally chronic pulmonary disease, usually either cancer or infection; in the pre-antibiotic era it was predominantly the latter. Biomolecular analyses indicate the presence of Mycobacterium tuberculosis DNA in one of the specimens, strongly indicating that pulmonary tuberculosis was the eliciting factor in this case. This is the first time that a primary cause for hypertrophic osteoarthropathy has been firmly identified in an ancient skeleton and illustrates the potential of a dual approach using both osteological and biomolecular techniques for enhancing our understanding of early disease. The other specimen proved negative for M. tuberculosis complex DNA, however the presence of infectious rib lesions allowed us to suggest that some non-tuberculous pulmonary infection was likely the primary cause of hypertrophic osteoarthropathy in this case. | ||||
Year of Publication The year the book, article or report was published |
2002 | ||||
Locations Any locations covered by the publication or report. This is not the place the book or report was published. |
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Source Where the record has come from or which dataset it was orginally included in. |
BIAB
(The British & Irish Archaeological Bibliography (BIAB))
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Created Date The date the record of the pubication was first entered |
14 Jan 2003 |