Hunnius, von, T. E., Yang, D. Y., Eng, B., Waye, J. and Saunders, S. (2007). Digging deeper into the limits of ancient DNA research on syphilis. J Archaeol Sci 34 (12). Vol 34(12), pp. 2091-2100.
 Title The title of the publication or report |
Digging deeper into the limits of ancient DNA research on syphilis | ||
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Issue The name of the volume or issue |
J Archaeol Sci 34 (12) | ||
Series The series the publication or report is included in |
Journal of Archaeological Science | ||
Volume Volume number and part |
34 (12) | ||
Page Start/End The start and end page numbers. |
2091 - 2100 | ||
Biblio Note This is a Bibliographic record only. |
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Publication Type The type of publication - report, monograph, journal article or chapter from a book |
Journal | ||
Abstract The abstract describing the content of the publication or report |
The paper aims to compliment and add relevant information to Bouwman and Brown's and Barnes and Thomas' discussion concerning the inability to apply ancient DNA techniques to study venereal syphilis in past human populations. The authors' approach utilized fifteen different human specimens from different geographies and different temporal periods: eight samples come from medically diagnosed individuals archived during the American Civil War period; six originate from the United Kingdom and predate 1492 with four of these samples having been previously analyzed by Bouwman and Brown, and one sample comes from historic Canada. Human mitochondrial and amelogenin DNA, as well as several genes from the Treponema organism were analyzed revealing the relatively good preservation of human multi-copy and single copy DNA but not treponemal DNA. The study also incorporates a unique molecular experiment using rabbits infected with venereal syphilis to help illustrate that treponemal DNA disseminates to bone early during the first stages of infection but is not present in later stages of the disease using the techniques presented in this study. | ||
Year of Publication The year the book, article or report was published |
2007 | ||
Locations Any locations covered by the publication or report. This is not the place the book or report was published. |
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Source Where the record has come from or which dataset it was orginally included in. |
BIAB
(The British & Irish Archaeological Bibliography (BIAB))
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Relations Other resources which are relevant to this publication or report |
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Created Date The date the record of the pubication was first entered |
25 Feb 2008 |
