Cattaneo, C., Gelsthorpe, K., Phillips, P. and Sokel, R. (1992). Detection of blood proteins in ancient human bone using ELISA: a comparative study of the survival of IgG and albumin. Internat J Osteoarchaeol 2 (2). Vol 2(2), pp. 103-107. https://doi.org/10.1002/oa.1390020202.

Title
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Title:		 Detection of blood proteins in ancient human bone using ELISA: a comparative study of the survival of IgG and albumin
Issue
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Issue:		 Internat J Osteoarchaeol 2 (2)
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Series:		 International Journal of Osteoarchaeology
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Volume:		 2 (2)
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Page Start/End:		 103 - 107
Biblio Note
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Publication Type:		 Journal
Abstract
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Abstract:		 The immunological identification of species-specific blood proteins in skeletal remains has an important role in the reconstruction of ancient dietary, ritual and domestic behaviour. However, which protein provides the most suitable target for such work has not been considered previously, and the present investigation was carried out on human bone to assess the relative merits of IgG and albumin. Extracts of bone from thirty one individuals (from the English Civil War, medieval, Early Saxon, Roman, Iron Age and Bronze Age periods) were tested by an enzyme-linked immunosorbent assay (ELISA) using monoclonal antibodies. Albumin was detected in 23 of the 31 skeletons, including those from the Iron and Bronze Ages, whereas IgG was identified in only one. The better detection rate for albumin was thought to be due to its higher original blood level, inherent differences in survival pattern being considered unlikely. Au(abr)
Author
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Author:		 Cristina Cattaneo
K Gelsthorpe
Patricia Phillips
R J Sokel
Year of Publication
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Year of Publication:		 1992
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Subjects / Periods:
Human Bone (Auto Detected Subject)
Bone (Auto Detected Subject)
Medieval Early Saxon Roman Iron Age (Auto Detected Temporal)
Skeletal Remains (Auto Detected Subject)
Iron (Auto Detected Subject)
Bronze Age (Auto Detected Temporal)
Ritual (Auto Detected Subject)
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BIAB (The British Archaeological Bibliography (BAB))
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DOI: https://doi.org/10.1002/oa.1390020202
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Created Date:		 20 Jan 2002