| Title: |
Non-random DNA damage resulting from heat treatment:
|
| Subtitle: |
implications for sequence analysis of ancient DNA |
| Issue: |
J Archaeol Sci 31 (1) |
| Series: |
Journal of Archaeological Science
|
| Volume: |
31
(1)
|
| Page Start/End: |
59 - 63 |
| Biblio Note |
Please note that this is a bibliographic record only, as originally entered into the BIAB database.
The ADS have no files for download, and unfortunately cannot advise further on where to access hard copy or digital versions.
|
| Publication Type: |
Journal
|
| Abstract: |
Results of an experiment to replicate damage occurring during preservation of ancient DNA. The authors anticipated that nucleotide changes indicating damage would be randomly distributed, but this was not the case. They propose that, if non-random sequence changes are a widespread feature of DNA degradation, then current strategies for analysis of ancient DNA sequences should be revised, as these could lead to nucleotide variations that are artefacts resulting from DNA diagenesis being mistaken for genuine sequence features of the ancient DNA. |
| Year of Publication: |
2004
|
| Subjects / Periods: |
|
Heat-Treatment
(BIAB)
|
|
Dna [Deoxyribo Nucleic Acid]
(BIAB)
|
|
| Source: |
BIAB
(The British & Irish Archaeological Bibliography (BIAB))
|
| Created Date: |
03 Dec 2004 |
