| Title: |
The limits of biomolecular palaeopathology:
|
| Subtitle: |
ancient DNA cannot be used to study venereal syphilis |
| Issue: |
J Archaeol Sci 32 (5) |
| Series: |
Journal of Archaeological Science
|
| Volume: |
32
(5)
|
| Page Start/End: |
703 - 713 |
| Biblio Note |
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|
| Publication Type: |
Journal
|
| Abstract: |
To determine whether ancient DNA (aDNA) can be used to study the palaeopathology of venereal syphilis, the authors carried out a comprehensive analysis of the preservation of human and pathogen DNA in a set of forty-six bones of various ages, most of which displayed osteological indications of the disease. Bones came from seven English cemetery sites that were in use during the ninth--nineteenth centuries. Failure to detect treponemal DNA in bones that were suitable for aDNA analysis, using highly sensitive polymerase chain reactions (PCRs), suggests that treponemal DNA is not preserved in human bone and that it is therefore not possible to use aDNA analysis to study venereal syphilis. |
| Year of Publication: |
2005
|
| Subjects / Periods: |
| English Cemetery (Auto Detected Subject) |
| Human Bone (Auto Detected Subject) |
| Fortysix Bones (Auto Detected Subject) |
|
| Source: |
BIAB
(The British & Irish Archaeological Bibliography (BIAB))
|
| Relations: |
|
| Created Date: |
29 Jun 2005 |
