Bouwman, A. S. and Brown, T. A. (2005). The limits of biomolecular palaeopathology:. J Archaeol Sci 32 (5). Vol 32(5), pp. 703-713.

Title
Title
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Title:
The limits of biomolecular palaeopathology:
Subtitle
Subtitle
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Subtitle:
ancient DNA cannot be used to study venereal syphilis
Issue
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Issue:
J Archaeol Sci 32 (5)
Series
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Series:
Journal of Archaeological Science
Volume
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Volume:
32 (5)
Page Start/End
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Page Start/End:
703 - 713
Biblio Note
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Journal
Abstract
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Abstract:
To determine whether ancient DNA (aDNA) can be used to study the palaeopathology of venereal syphilis, the authors carried out a comprehensive analysis of the preservation of human and pathogen DNA in a set of forty-six bones of various ages, most of which displayed osteological indications of the disease. Bones came from seven English cemetery sites that were in use during the ninth--nineteenth centuries. Failure to detect treponemal DNA in bones that were suitable for aDNA analysis, using highly sensitive polymerase chain reactions (PCRs), suggests that treponemal DNA is not preserved in human bone and that it is therefore not possible to use aDNA analysis to study venereal syphilis.
Author
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Author:
Abigail S Bouwman
Terence (Terry) A Brown
Year of Publication
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Year of Publication:
2005
Locations
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Subjects / Periods:
English Cemetery (Auto Detected Subject))
Human Bone (Auto Detected Subject))
Fortysix Bones (Auto Detected Subject))
Source
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Source:
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BIAB (The British & Irish Archaeological Bibliography (BIAB))
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URI: http://www.sciencedirect.com/science/journal/03054403
Created Date
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Created Date:
29 Jun 2005